PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G53170.1
Common NameATERF8, ATERF-8, ERF079, ERF8, ERF-8, F12M16.6
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 185aa    MW: 20024.8 Da    PI: 9.7802
Description ethylene response factor 8
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G53170.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2591.2e-183079255
          AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                 +y+GVr ++ +gr++AeIrdp++   ++r++lg+f+ta++Aa+a++aa++ ++g
  AT1G53170.1 30 RYRGVRKRP-WGRYAAEIRDPVK---KTRVWLGTFDTAQQAARAYDAAARDFRG 79
                 59*******.**********654...5**********************98876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103223.2883087IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.1E-303086IPR001471AP2/ERF domain
PfamPF008472.8E-123078IPR001471AP2/ERF domain
SMARTSM003801.4E-343093IPR001471AP2/ERF domain
SuperFamilySSF541712.42E-213088IPR016177DNA-binding domain
CDDcd000184.51E-193086No hitNo description
PRINTSPR003673.5E-113142IPR001471AP2/ERF domain
PRINTSPR003673.5E-115369IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025034anatomyleaf
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007131developmental stageseedling development stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 185 aa     Download sequence    Send to blast
MPNITMGLKP DPVAPTNPTH HESNAAKEIR YRGVRKRPWG RYAAEIRDPV KKTRVWLGTF  60
DTAQQAARAY DAAARDFRGV KAKTNFGVIV GSSPTQSSTV VDSPTAARFI TPPHLELSLG  120
GGGACRRKIP LVHPVYYYNM ATYPKMTTCG VQSESETSSV VDFEGGAGKI SPPLDLDLNL  180
APPAE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A5e-192692168ATERF1
3gcc_A5e-192692168ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.46040.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO425627210.0
Genevisible261315_at0.0
Expression AtlasAT1G53170-
AtGenExpressAT1G53170-
ATTED-IIAT1G53170-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-1 of ERF/AP2 transcription factor family (ATERF-8). The protein contains one AP2 domain. There are 15 members in this subfamily including ATERF-3, ATERF-4, ATERF-7, and leafy petiole.
UniProtInvolved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Acts as a transcriptional inhibitor and may regulate other AtERFs (By similarity). {ECO:0000250, ECO:0000269|PubMed:11487705}.
Function -- GeneRIF ? help Back to Top
  1. AtERF4 and AtERF8 regulated the expression of many genes involved in the progression of leaf senescence.
    [PMID: 23629833]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00202DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G53170.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9MAI5
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G53170
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0368840.0AB036884.1 Arabidopsis thaliana AtERF8 mRNA for ERF transcription factor8, complete cds.
GenBankAC0080070.0AC008007.7 Genomic sequence for Arabidopsis thaliana BAC F12M16 from chromosome I, complete sequence.
GenBankAC0225200.0AC022520.2 Arabidopsis thaliana chromosome I BAC F8L10 genomic sequence, complete sequence.
GenBankAK1175410.0AK117541.1 Arabidopsis thaliana At1g53170 mRNA for putative ethylene responsive element binding factor 8 (ERF8), complete cds, clone: RAFL17-19-H19.
GenBankBT0054010.0BT005401.1 Arabidopsis thaliana clone U50346 putative ethylene responsive element binding factor 8 (At1g53170) mRNA, complete cds.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_175725.11e-136ethylene-responsive transcription factor 8
SwissprotQ9MAI51e-138ERF79_ARATH; Ethylene-responsive transcription factor 8
TrEMBLD7KKE63e-96D7KKE6_ARALL; Putative uncharacterized protein
STRINGAT1G53170.11e-136(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Ohta M,Matsui K,Hiratsu K,Shinshi H,Ohme-Takagi M
    Repression domains of class II ERF transcriptional repressors share an essential motif for active repression.
    Plant Cell, 2001. 13(8): p. 1959-68
    [PMID:11487705]
  3. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
    [PMID:11910074]
  4. Bray EA
    Classification of genes differentially expressed during water-deficit stress in Arabidopsis thaliana: an analysis using microarray and differential expression data.
    Ann. Bot., 2002. 89 Spec No: p. 803-11
    [PMID:12102506]
  5. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  6. Hu W,Wang Y,Bowers C,Ma H
    Isolation, sequence analysis, and expression studies of florally expressed cDNAs in Arabidopsis.
    Plant Mol. Biol., 2003. 53(4): p. 545-63
    [PMID:15010618]
  7. Wang J, et al.
    Genomewide nonadditive gene regulation in Arabidopsis allotetraploids.
    Genetics, 2006. 172(1): p. 507-17
    [PMID:16172500]
  8. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  9. Nemhauser JL,Hong F,Chory J
    Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.
    Cell, 2006. 126(3): p. 467-75
    [PMID:16901781]
  10. Jung J, et al.
    The barley ERF-type transcription factor HvRAF confers enhanced pathogen resistance and salt tolerance in Arabidopsis.
    Planta, 2007. 225(3): p. 575-88
    [PMID:16937017]
  11. Lee J, et al.
    Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development.
    Plant Cell, 2007. 19(3): p. 731-49
    [PMID:17337630]
  12. Yamamoto YY, et al.
    Identification of plant promoter constituents by analysis of local distribution of short sequences.
    BMC Genomics, 2007. 8: p. 67
    [PMID:17346352]
  13. Dombrecht B, et al.
    MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis.
    Plant Cell, 2007. 19(7): p. 2225-45
    [PMID:17616737]
  14. Dortay H, et al.
    Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana.
    J. Proteome Res., 2008. 7(9): p. 3649-60
    [PMID:18642946]
  15. Chen YY,Wang LF,Dai LJ,Yang SG,Tian WM
    Characterization of HbEREBP1, a wound-responsive transcription factor gene in laticifers of Hevea brasiliensis Muell. Arg.
    Mol. Biol. Rep., 2012. 39(4): p. 3713-9
    [PMID:21761140]
  16. Son GH, et al.
    Ethylene-responsive element-binding factor 5, ERF5, is involved in chitin-induced innate immunity response.
    Mol. Plant Microbe Interact., 2012. 25(1): p. 48-60
    [PMID:21936663]
  17. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  18. Koyama T, et al.
    A regulatory cascade involving class II ETHYLENE RESPONSE FACTOR transcriptional repressors operates in the progression of leaf senescence.
    Plant Physiol., 2013. 162(2): p. 991-1005
    [PMID:23629833]
  19. Lumba S, et al.
    A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis.
    Dev. Cell, 2014. 29(3): p. 360-72
    [PMID:24823379]
  20. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]